Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Rose McGowan accused producer Harvey Weinstein of rape this time last year, sparking an avalanche of allegations in the entertainment industry and beyond.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
韦斯·安德森(Wes Anderson)的每部电影似乎都存在于它自己的世界里。《布达佩斯大饭店》(The Grand Budapest Hotel)以20世纪30年代为背景，通过独特的元素和道具定义它的世界。
The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.
Foreign property investment by Chinese companies plunged by 84 per cent last month, as Beijing’s capital controls choked off the flow of foreign acquisitions.
Trends and targets in antiviral phototherapy
Ahead of this year's fashion week, set to take place September 14 to 18, an open letter written by singer Paloma Faith and published by Peta also called for LFW and the BFC to ban animal fur.
The next step? Jalava plans to upgrade the finger with an RFID tag and add wireless support. He also wants to add more memory, which seems pointless to us. If he needs more storage, he has nine other fingers he can chop off and replace with flash drives.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The Lord of the Rings trilogy. The amount of time before I need an oil change. My cell phone's battery charge. What do all of these things have in common? The
ACE2 as a potential therapeutic target for pandemic COVID-19
米兰达·兰伯特，《浴室水槽》(Bathroom Sink)，RCA Nashville
Diagnostic technologies for COVID-19: a review
欧盟外交政策高级代表费代丽卡?莫盖里尼(Federica Mogherini)和欧盟扩大事务专员约翰内斯?哈恩(Johannes Hahn)也表明立场，批评埃尔多安提议的宪法改革及其最近的言辞。
A median forecast from economists had predicted a 0.9 per cent rise.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Logan's claws are slow on the draw and his self-healing powers are on the fritz, but he's committed to caring for his mentor Charles Xavier (Patrick Stewart, so good you want to applaud). It's not easy watching Professor X suffer seizures that rattle his telepathic brain. Make no mistake, Logan earns its tears. If Jackman and Stewart are serious about this being their mutual X-Men swan song, they could not have crafted a more heartfelt valedictory.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
At the age of 12, most girls are battling with their parents to get their ears pierced, learning the ropes at senior school and preparing for life as a teenager.
And, this year, Star Wars found its way onto the list as well, with ‘starwars’ claiming the 16th spot.
World Health Organisation declared that the cluster of microcephaly cases and other neurological disorders were a public health emergency of international concern, it was a rallying cry for the international community to respond.
Influenza neuraminidase: A druggable target for natural products
都柏林大学学院(UCD)迈克尔?斯墨菲特商业研究生院(Michael Smurfit Graduate School of Business)的总体进步最大，排名攀升21位至第48名。北京大学(Peking University)光华管理学院(Guanghua School of Management)重回排行榜第38名，去年该院因学员调查反馈率低而未上榜。
Further, 32 out of the 50 new selected female billionaires started their businesses from scratch.
I experienced this pessimism personally in Davos in January 2014. Several leading western intellectuals asked me whether war would break out between China and Japan. I was so confident that there would be no war in east Asia that I offered to take bets with ten-to-one odds against myself with eminent western journalists. Two took up my bets. And I will be collecting on these bets when I return to Davos in January.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Comparing regions within specific categories of costs, the EIU notes that Asian cities are the most expensive for grocery shopping, with Seoul in South Korea the priciest for food. European cities are the most expensive in terms of recreation and entertainment.
The role of biosensors in the detection of emerging infectious diseases
The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
We first see the hair of Anna Morales (Jessica Chastain) during the opening credits of “A Most Violent Year.” She’s at her makeup mirror.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
You’re a busy person. At times, it all can feel overwhelming. Asana is a cloud-based project management software that helps you keep it together. (Trust me, I’ve tried them all.) Flexibility is built into Asana’s architecture. Each “task”, or “subtask”, can be associated with a larger “project” and “department.” In addition, you can even assign recurring tasks to yourself or team, which makes life so much easier. Stop trying to remember all the things you’re supposed to do and let Asana structure your life.
Attractions: Europe’s underrated gem.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The life expectancy of the average human has increased more in the past 50 years than it did in the 200,000 years of human existence. Life expectancy is now 70 years old – which is a big difference from 47 years old in 1950!
On Her Majesty's Secret Service gets an honorable mention on our list of James Bond Theme songs.
Of the graduates to have been through the scheme, 42 per cent have not persisted with teaching. But Teach First says even those who have left the profession remain loyal to the programme’s values.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
John Hummel, chief investment officer for AIS Group, a fund manager with $400 million under management, said all the new sources of global oil are expensive to extract, and he sees U.S. shale output falling by 2015.
We will promote the liberalization and facilitation of international trade and investment.
Inhibition of SARS coronavirus helicase by bismuth complexes
Her mother Stephanie Boyden, 32, says Bobbi is a 'diva' who runs to the stage when her name is called - and screams when she has to leave.
37| “Anomalisa” (Charlie Kaufman/Duke Johnson)|
We were forced to leave our comfort zone but were rewarded with unique experiences, says one graduate.
The prize sold for far more than the gallery's estimate of $50,000 to $100,000. The only other Nobel Peace Prize known to have sold at auction was a 1903 medal that brought nearly $17,000 in 1985.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
More advanced components are in short supply, however, which could leave many customers waiting long after September to get hold of the new iPhone. That presents an opportunity for rivals such as Samsung’s new Note 8 or Essential, the smartphone maker led by Android co-founder Andy Rubin, which is targeting premium customers such as Apple’s with its slick $699 device. Google is also said to be preparing a new version of its Pixel smartphone, which has proved popular with early adopters.
10.You are Stressed All the Time
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
"Hiring a veteran can be one of the best decisions any of us can make, and Wal-Mart is proud that we have hired more than 26,000 since we announced our Welcome Home Commitment on Memorial Day," Simon told Fortune. "Veterans have a strong record of performance under pressure and passion for service, which makes our pledge to hire, learn from, and support them easy."
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
9.We here in the UK want nothing more than to provide you, our guests, with a fantastic experience this summer, combining the best in international sport, brilliant facilities, fantastic entertainment and a cultural legacy that draws on centuries of excellence in art and architecture. If you ended up with four tickets for the wrestling at the ExCel Centre, well, better luck next time.
“Policymakers around the world are cognisant of the impact the Fed decision will have and are worried, which makes us worried,” said Simon Lue-Fong, head of global emerging debt at Pictet Asset Management. “People are saying the decision is priced in but seeing as no one knows exactly what will happen how can that possibly be true.”
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
The Suicide Squad is scheduled for an August 5th 2016 release.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Turn your work in on time. If extra credit work is offered, do that too.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
China has made huge progress in easing its residence and entry policies for foreigners since September 2015, which has helped attract more talent from overseas, as well as boost international exchanges and the economy, according to a ministry statement.
Even if Asian countries introduced regulation similar to that of thriving ETF markets elsewhere in the world, there are other hurdles. Mr Montanari says, for example, that most products presented to Asian investors relate to equities in their domestic market so the ETFs are not being used to give investors local exposure to foreign markets.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Financial advisors and asset allocators who had been hoping to see some benefit this year from tactical strategies were also not spared the punishment of a capricious market. Of the top three tactical strategies in the country (Mainstay Marketfield, Good Harbor U.S. Tactical Core, F-Squared Premium AlphaSector Index), two had nearly imploded with double-digit losses while the third found itself under SEC investigation for misleading the public about its historical returns. The other giant tactical manager, Schwab’s $9 billion Windhaven Diversified Growth product, looks to end 2014 with a return close to zero. So much for tactics.
The local court gave Zhou a lenient sentence due to the teenager's age and frank confession of the crime, according to the report.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Are you often irritable?
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
从“高跟鞋门”到“金棕榈狗狗奖”（Palm Dog），再到迅速走红的“老爹身材（Dad bod）”，戛纳电影展的这12天，真是令人眼花缭乱。随着电影节进入尾声，英国广播公司回顾了本届戛纳影展上的九桩事。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
But Choupette isn't only a kept kitty, for she made more than ￡2.3million in one year alone after appearing in just two ad campaigns — one for Japenese beauty product Shu Uemura, and for German car company Vauxhall.
He then pressed all the buttons in the hope to get the elevator to work again, but to no avail. Sun then punched the "stop" button, to lock the elevator and secure it won't move.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Over the three-year period we examined, late arrivals actually declined during the Thanksgiving travel season — just 12 percent of Thanksgiving flights were delayed last year, compared with 19 percent in 2010. according to the Transportation Department.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Season\'s greetings and best wishes for the New Year.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
The survey discusses projections for going forward: "The cost of living is always changing and there are already indications of further changes that are set to take place during the coming year."
It is a struggle for power contained by understandings and institutions.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
High and rising US rates may quickly become drivers of EM crises: such conditions may lead to higher borrowing costs in EMs, along with capital outflows and an unwillingness by the financial sector to take risks.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
埃米?珀勒(Amy Poehler)狂吻博诺(Bono)，蒂娜?费(Tina Fey)吐槽乔治?克鲁尼(George Clooney)只爱年轻女人，而诡异的是马特?戴蒙(Matt Damon)当晚数次“中枪”。
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
The CSI 300, which consists of 300 of the top A-shares traded on the Shanghai and Shenzhen exchanges, is down 7 per cent and will be shut for the remainder of the day.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Criminal gangs have been difficult to catch, however, because illegal meats are often hidden among other produce such as fruit and vegetables, and lorry drivers are often bribed to deny any knowledge of it.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
"We are also witnessing a positive progress of diversification," he said. "In the past, most Chinese companies' patent filings were concentrated in the ICT sector, but now there are increasingly patents filed in engines, turbines, sports, automotive, and biotechnology sectors."
A facile assay for rapid detection of COVID-19 antibodies
BATTLE CREEK (CBS, March 1) What a difference a hit makes. Vince Gilligan wrote a pilot script for this frenemy-cop show more than a decade ago, before he was Vince Gilligan, creator of “Breaking Bad” (and “Better Call Saul”). Now it’s being made into a series with a 13-episode guarantee from CBS. Dean Winters (“Law & Order: SVU,” “30 Rock”) plays a local detective and Josh Duhamel (“Las Vegas”) a slick F.B.I. agent who work together, uneasily, in the Cereal City of Battle Creek, Mich.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
2015年英国《金融时报》全球高管工商管理硕士课程(Global Executive MBA，简称全球EMBA)排行榜由于两个原因而引人注目。不仅因为这是英国《金融时报》发布的第100个商学院排行榜，也是因为今年首次有一个主办方包含一所中国内地商学院的项目拔得头筹。
LBS moves back to the top place, thanks in part to the highest salary, at $167,000, and being second best in value-for-money terms. The school is first for international course experience and second for alumni mobility.
In this case, the Lakers got a reasonable return for their top trade piece, prepared to give their young players like D'Angelo Russell and Brandon Ingram greater responsibilities down the stretch, and hunkered down for a tank that just might land UCLA star Lonzo Ball.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
IE’s alumni have the second-highest average salary increase following graduation, at 39 per cent. The school is ranked first for aims achieved and for international mobility. It is third for career progress. “There is a definite ‘before and after’ for career progression,” says one former student. “Post-MBA I felt I had more of a sense of direction not only of where I wanted to be, but also why, and how to make it happen.”
The average price for new residential housing rose 12.6 per cent in November year on year, according to a weighted average from Reuters based on data for 70 major cities published by the National Bureau of Statistics. That is up just 0.3 percentage points from October, whereas previous months had frequently seen jumps of 1 or 2 percentage points at a time.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
另外，Dua Lipa想要冲击三个奖项的，最后拿到了最佳艺人奖。虽然Harry Styles可能是One Direction最时尚的成员之一，但这位具有时代标志的歌手的皇冠意外地被MTV EMA的新人和前乐队的伴侣ZAYN抢走了。
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Horowitz admitted that while doing so he has had to work carefully to preserve 007's characters and attitude as created by the spy novel’s first author Ian Fleming, who died in 1964.
Length-scale dependence of protein hydration-shell density
200911/88512.shtmlA love letter to a US college student from the girlfriend who was to become his wife is finally on its way to him - 53 years after it was written in 1958.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
在这两个新指标方面，英国商学院的表现都优于法国商学院。在职业发展方面表现最好的英国商学院——华威商学院(Warwick Business School)在这一指标的总体排名中位居第二，高于法国在这方面表现最好的巴黎高等商学院(HEC Paris) 30个名次。在毕业后首份工作薪资与当下薪资比较方面，英国商学院校友的薪资增幅更大，为62%，法国商学院校友的薪资增幅为45%。然而，英国商学院校友的平均薪资仍低于与法国商学院校友，分别为5.5万美元和6.4万美元。
HEC Paris and London Business School have tightened their grip on the top of the Financial Times rankings of pre-experience and post-experience Masters in Finance programmes respectively, having dominated the finance rankings since they were first published in 2011.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
More than 430,000 students from 1,767 universities in 31 provinces, municipalities and autonomous regions across China were surveyed. Of the respondents, 89.2% had considered starting a business, with 18.2% reporting firm intentions to do so.
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200911/88512.shtml1977：“俄罗斯型流感”H1N1感染人类1977: "Russian flu" H1N1 Infects Humans